Currently (October 2020), the XE3 version of Q++Studio supports QuarkXPress versions, from QuarkXPress 5 to QuarkXPress 2020, inclusively.
However, not all versions of QuarkXPress are supported by all versions of Windows, and vice-versa.
Quark-Windows Restrictions and Incompatibilities
•QuarkXPress 5-6-7 can only run on Windows XP.
•QuarkXPress 8 can only run on Windows XP and Windows 7 (not on Windows 10).
•QuarkXPress 2019-2020 can only run on Windows 10.